Arizona Cardinals Home: The official source of the latest Cardinals headlines, news, videos, photos, tickets, rosters and game day information

San Francisco 49ers at Arizona Cardinals, December 27, 2020

Arizona seeks to extend its home streak against the 49ers. The Cardinals have won five of its last six home games and holds an 8-6 edge at State Farm Stadium against the 49ers.

WEEK 16 • SUN 12/27 • 11:00 AM MST

San Francisco 49ers 1 - 1

1 - 1

Arizona Cardinals 2 - 0

2 - 0

History: San Francisco 49ers at Arizona Cardinals

  • All Time Record: The Cardinals are 26-31 against the 49ers in the regular season.
  • Interesting Fact: Kyler Murray (twice) and Drew Brees were the only quarterbacks to post a 100+ passer rating against the 49ers last season, and his 130.7 passer rating in Week 9 is the highest by a Cardinals quarterback in 57 meetings against San Francisco.
  • Streaks: The Cardinals have won eight of the last 10 meetings.
  • 2019 Results: The 49ers won both meetings in 2019. They defeated the Cardinals at State Farm Stadium 28-25 on Thursday Night Football (October 31). On November 17, the 49ers beat the Cardinals 36-26 at Levi's Stadium.

Players and Coaches to Know

San Francisco 49ers

Arizona Cardinals

A chronological look at the Cardinals' ninth regular season game against the 49ers