Selected by the Cardinals in the first round (24th overall) of the 2015 NFL Draft, Humphries started 43 games – 33 at LT and 10 at RT – in his first five NFL seasons. Signed a three-year contract with Arizona on 2/18/20.
2019: Started all 16 games at LT for the NFL's 10th-ranked rushing offense (1,990 yards) that averaged a single-season franchise-record 5.03 yards per carry (second in the NFL) ... part of a unit that gained 514 total yards and 266 rushing yards @ Cin (10/6), the most by a Cardinals offense since 12/6/15 @ StL (524) and 11/27/11 @ StL (268), respectively; blocked for Kyler Murray (93), David Johnson (91) and Chase Edmonds (68) who formed the first trio of Cardinals players to rush for 60+ yards in a game since 10/19/75 vs. Phi ... helped the offense gain 442 total yards including 340 passing yards vs. Atl (10/13); part of an O-line that did not permit a sack, allowing Murray to complete 27-of-37 passes for 340 yards, three TDs and a 128.2 passer rating against the Falcons ... part of a Cardinals rushing attack that gained 156 yards and scored three TDs on 38 carries in rainy conditions @ NYG (10/20); helped lead Edmonds to the end zone on 20, 20 and 22-yard carries, marking the first time in franchise history – and just the sixth time in NFL history – a player had at least three rushing TDs of 20+ yards in a game ... part of an offense that scored 25 points and three TDs, gained 357 total net and 153 rushing yards and averaged 7.1 yards per play and 7.6 yards per pass attempt on Thursday Night Football vs. SF (10/31), all representing season highs allowed by the NFL's #1-ranked defense through Week 9 ... protected Murray, who threw for 324 yards and three TDs on 27-of-44 passing @ TB (11/10) ... part of an offensive unit that tallied season highs with 38 points, six scoring drives, five TDs, four rushing TDs, 7.4 yards per play and 26 first downs while not allowing a sack vs. Cle (12/15); helped lead Kenyan Drake to 137 rushing yards and a career-high four rushing TDs, the most by a Cardinals player since Ronald Moore had four vs. LAR (12/5/93) ... part of an offense that gained 412 total net yards and 253 rushing yards @ Sea (12/22), marking the first time since 1982 the Cardinals rushed for 200+ yards in consecutive games.
2018: Played every offensive snap at LT in Games 1-9 for a unit that started 10 different offensive line combinations throughout the season … one of seven Cardinals offensive lineman to suffer a season-ending injury … helped David Johnson into the end zone with two rushing TDs and blocked for Josh Rosen, who was sacked just once @ SF (10/7) … gave Rosen time to find Christian Kirk for the go-ahead TD on third-and-goal with 34 seconds left in the game vs. SF (10/28) … inactive (knee) vs. Oak (11/18), @ LAC (11/25) and @ GB (12/2) … placed on injured reserve (knee) on 12/5.
2017:Started five games at LT, missing Weeks 2-5 and 11-17 with a knee injury … made his fourth career start at LT but suffered a knee injury on the eighth offensive play of the game @ Det (9/10) … returned from the injury and helped Adrian Peterson rush for 134 yards and two TDs on 26 carries vs. TB (10/15) … started for an offensive line that did not permit a sack and helped Peterson rush for 159 yards on a franchise-record 37 carries @ SF (11/5) … suffered a season-ending knee injury in the first quarter vs. Sea (11/9) … placed on injured reserve on 11/13.
2016: Started first 13 games (first 10 at RT, next three at LT) before suffering a concussion and missed the last three games … helped the Cardinals score 418 points (fourth-most in franchise history) and finish as the NFL's #9 ranked offense … made first career appearance in the season opener and helped gain 92 rushing yards and a TD on 19 attempts vs. NE (9/11) … helped Arizona run for 118 yards on 25 carries vs. LAR (10/2) … contributed to a line that helped Cardinals rush for 172 yards and two TDs on 37 attempts while allowing just one sack @ SF (10/6) … blocked as Cardinals ran for 171 yards and three TDs on 35 carries while not allowing a sack vs. NYJ (10/17) … helped Arizona rush for 132 yards on 37 attempts vs. Sea (10/23) … blocked as Cardinals rushed for 135 yards and a TD on 28 carries @ Min (11/20) … made first career start at LT @ Atl (11/27) … started at LT but left in the first half with a concussion @ Mia (12/11) … inactive (concussion) the last three games.
2015:Â Inactive for all 16 regular season games and both playoff contests.
Appeared in 29 games (19 starts) at LT before declaring for the NFL Draft following his junior season … started all 10 games in which he appeared at LT in 2014, missing two games due to injury … Gators rushed for 100+ yards in all 10 games he played, including four games with 200+ yards and a season-best 418 yards on the ground vs. Georgia … Florida also posted 20 rushing TDs in his 10 games … helped the offense accumulate 655 net yards of offense and seven TDs in a 65-0 victory over Eastern Michigan in the season opener … part of an offensive line that allowed one sack or fewer in six of 10 games he started, including four games with no sacks … played in seven games as a sophomore, starting the first six at LT, before a knee injury ended his season … in the six games he started, the Gators averaged 178.5 rushing yards per game, compared to 113.0 rushing yards per game in the six games he did not start … team averaged more than 100 fewer net yards per game in the games he did not start (367.8 ypg vs. 265.5 ypg) … appeared in all 12 games (three starts) as a true freshman and was named to the SEC Coaches All-Freshman team and was a Sporting News Freshman All-American … enrolled in January of 2012.
Attended Mallard Creek (Charlotte, NC) High School, where he was named a first-team high school All-American by USA Today, ESPN, Rivals.com, MaxPreps and Sports Illustrated … started all four seasons and did not allow a sack over the final three years of his prep career … led Mallard Creek to a 13-1 record and berth in the NCHSAA Class 4AA State Semifinals … named an AP All-State first-team selection … selected to participate in the 2012 U.S. Army All-America Bowl … serves as a spokesperson for the NFL's Fuel Up To Play 60 program partnering with the Dairy Council of Arizona ... married his wife, Briyana, during the 2020 offseason.