- Selected by Arizona with their second pick of the third round (100th overall) of the 2022 NFL Draft out of Cincinnati. He became just the sixth Bearcat player ever drafted by Arizona, and just the second defensive player.
- Appeared in 13 games (4 starts) as a rookie in 2022 and totaled 23 tackles, three tackles for loss, 3.0 sacks, five QB hits, three passes defensed, a forced fumble and a fumble recovery.
- Had a standout performance in the Cardinals victory vs. the Rams in Week 10 last season, finishing with five tackles, a sack, his first career forced fumble, a tackle for loss and a pass defensed. The performance earned him his first career game ball.
- A two-time first-team American Athletic Conference selection (2020-21), Sanders finished the 2021 season with 62 total pressures, which led the AAC.
- In 2020, was a semifinalist for the Bednarik Award as the best defensive player in college football. He finished that season with 31 tackles, 10.5 tackles for loss, 7.0 sacks and five passes defensed in just 10 games.