Cardinals safety Antoine Bethea celebrates after the first of his two interceptions on Sunday.
Antoine Bethea set a career-high with his fifth interception of the season on Sunday against the Giants, but that's where the total will remain.
The Cardinals' safety tore a pectoral muscle in the 23-0 win and won't play in the regular season finale against the Seahawks. Bethea picked off Eli Manning twice in the contest, his first career multi-interception game.
Bethea was a steady presence in the secondary this season, leading the team in interceptions while mentoring rising star Budda Baker. Harlan Miller is expected to be the third safety in nickel packages alongside Baker and Tyrann Mathieu. Cornerback Justin Bethel could also get work in personnel groups that include five or six defensive backs.
"We've got plenty of guys," Arians said. "Taking five interceptions out of there is tough, though. Great season."
Bethea was placed on injured reserve Tuesday and linebacker Edmond Robinson was elevated from the practice squad in a corresponding move. Bethea is the third safety to be lost for the year, joining Tyvon Branch and Rudy Ford, and is the latest casualty in a season dominated by injuries. At this point, Arians said it's become so commonplace that the team shrugs it off.
"It's easy when you get the fifth, sixth, seventh, eighth, ninth, tenth injuries," Arians said. "It's really hard when you get the first four. It's like, 'Oh, here we go again.' It's doom and gloom around the team for a week or so. Now it's just, 'OK, who is it this week?' You pick up the pieces and you go."
Miller is a former cornerback who was pressed into emergency duty at safety last season when Tony Jefferson was injured in Week 16 in Seattle. Miller moved to safety this offseason because of his performance in that game and the season finale against the Rams, where he had an interception. Miller has been on the practice squad most of the year but Arians expressed confidence in him.
"He played up there last year and did a good job," Arians said.
Bethea, 33, signed a three-year free agent contract with the Cardinals this offseason and Arians believes he has plenty left in the tank.
"'Toine is still young, and he stays in great shape," Arians said. "He should have another great year next year."
Images from the Week 16 matchup at University of Phoenix Stadium
![RB Kerwynn Williams](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/xl3q0drdczvdebufxpok.jpg)
RB Kerwynn Williams
!["Merry Fitzmas"](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/rxpa5r1oy9bkz2aei22h.jpg)
"Merry Fitzmas"
![WR Larry Fitzgerald](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/qcbbp40hqboyvajdshf2.jpg)
WR Larry Fitzgerald
![Chandler Jones fans](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/tmqvohz2gtiagkzk4cmy.jpg)
Chandler Jones fans
![Cardinals QB Drew Stanton](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/otzmkcbadtb1vi1sqjq5.jpg)
Cardinals QB Drew Stanton
![Cardinals cheerleaders perform](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/mix6a7tjauvnwzudpc1a.jpg)
Cardinals cheerleaders perform
![WR Larry Fitzgerald](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/fmelfzak0nyspnhylv71.jpg)
WR Larry Fitzgerald
![Giants DT Damon Harrison](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/toos4b7mufhkxhpdncoc.jpg)
Giants DT Damon Harrison
![QB Drew Stanton](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/peee1kvihn1f5zzrn94m.jpg)
QB Drew Stanton
![Fans at the game](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/ndrw5zfiefdstsydkxud.jpg)
Fans at the game
![WR Larry Fitzgerald](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/xvxhghowhcibxo8acxte.jpg)
WR Larry Fitzgerald
![Coach Bruce Arians](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/l1bgyws7e7vifrldfjxt.jpg)
Coach Bruce Arians
![A fan dressed up at the game](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/ofrsr44f30p2pfhzevma.jpg)
A fan dressed up at the game
![Cardinals cheerleaders perform](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/kjpn4kxhwmzkplc2wqek.jpg)
Cardinals cheerleaders perform
![Fans at the game](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/gwkwv1vv0sbzpblsnuh2.jpg)
Fans at the game
![Cardinals cheerleaders perform](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/qw63fcbghq0ph9rbazkd.jpg)
Cardinals cheerleaders perform
![CB Patrick Peterson pregame](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/gqofz3lfi3rubw175v5w.jpg)
CB Patrick Peterson pregame
![Singer and Cardinals fan Jordin Sparks performs the national anthem](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/n9arpw6hwcbd6fpgipsh.jpg)
Singer and Cardinals fan Jordin Sparks performs the national anthem
![QB Drew Stanton](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/n8xbvkcfydxtjdhq2rx2.jpg)
QB Drew Stanton
![Giants RB Wayne Gallman](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/cbaln6bm4w95vmwjs3a6.jpg)
Giants RB Wayne Gallman
![S Antoine Bethea snags an interception](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/z8woimztnoqbuywhfgx3.jpg)
S Antoine Bethea snags an interception
![Cardinals head coach Bruce Arians directs from the sideline](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/nhimunwdx9vrqativfth.jpg)
Cardinals head coach Bruce Arians directs from the sideline
![The Cardinals defense swarms on Giants QB Eli Manning](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/kgecn7joy9pwzk5cyesw.jpg)
The Cardinals defense swarms on Giants QB Eli Manning
![Cardinals head coach Bruce Arians](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/tkc1wyufdxxbawtkexbg.jpg)
Cardinals head coach Bruce Arians
![Cardinals LB Deone Bucannon breaks up a pass intended for Giants WR Roger Lewis Jr.](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/hslvztchakv4gg0tlcs2.jpg)
Cardinals LB Deone Bucannon breaks up a pass intended for Giants WR Roger Lewis Jr.
![Cardinals fans show their love for Larry Fitzgerald](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/uf5dpzuwgu21xbsdgs1u.jpg)
Cardinals fans show their love for Larry Fitzgerald
![Cardinals K Phil Dawson with the kick attempt](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/fpgodgo589nlqeq42zem.jpg)
Cardinals K Phil Dawson with the kick attempt
![WR Larry Fitzgerald makes a tough catch on a flea-ficker](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/rowsjx3b0ez803qzdh1r.jpg)
WR Larry Fitzgerald makes a tough catch on a flea-ficker
![Cardinals DL Rodney Gunter rushes Giants QB Eli Manning](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/lfkkmyvqulexmnehlduf.jpg)
Cardinals DL Rodney Gunter rushes Giants QB Eli Manning
![S Antoine Bethea breaks up a pass intended for Giants WR Sterling Shepard](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/nro8qgwo1q1c78dzm8px.jpg)
S Antoine Bethea breaks up a pass intended for Giants WR Sterling Shepard
![Cardinals WR Larry Fitzgerald with the catch](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/rnxm1icbcyzr2cljmzzg.jpg)
Cardinals WR Larry Fitzgerald with the catch
![Giants QB Eli Manning](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/vx3idcbmjxf106hwsldi.jpg)
Giants QB Eli Manning
![Cardinals QB Drew Stanton](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/iwlqoeey1bt13fypvkwx.jpg)
Cardinals QB Drew Stanton
![Cardinals WR Larry Fitzgerald darts across the field after the catch](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/seyfptlmdsxpgvi7ldp9.jpg)
Cardinals WR Larry Fitzgerald darts across the field after the catch
![Cardinals WR Jaron Brown with the reception](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/vz0idgzgnfodcsrxssbu.jpg)
Cardinals WR Jaron Brown with the reception
![Cardinals head coach Bruce Arians speaks with his quarterback Drew Stanton](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/jn1cv81qh4ea20n55mq4.jpg)
Cardinals head coach Bruce Arians speaks with his quarterback Drew Stanton
![Giants QB Eli Manning fumbles the football](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/dbmc5kua8zygicfarwue.jpg)
Giants QB Eli Manning fumbles the football
![Larry Fitzgerald celebrates with G Alex Boone after scoring a touchdown](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/pnwieeplcvrtdhok7b3o.jpg)
Larry Fitzgerald celebrates with G Alex Boone after scoring a touchdown
![Giants TE Jerell Adams makes the grab](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/r0anfshwkrgrxpmuxmso.jpg)
Giants TE Jerell Adams makes the grab
![Cardinals DL Frostee Rucker](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/pmhuljuycmfo09ux8apc.jpg)
Cardinals DL Frostee Rucker
![Cardinals WR John Brown with the touchdown](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/siqzooqwtyvmnhvnj4m5.jpg)
Cardinals WR John Brown with the touchdown
![Cardinals RB Kerwynn Williams on the carry](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/hxguaehidzksl6ydlz0e.jpg)
Cardinals RB Kerwynn Williams on the carry
![Cardinals WR Larry Fitzgerald makes the catch](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/zthv00wj9dwdathym1xg.jpg)
Cardinals WR Larry Fitzgerald makes the catch
![QB Eli Manning with the throw](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/ofkugrdbtrrf9cygv85h.jpg)
QB Eli Manning with the throw
![The Giants and Cardinals at the line of scrimmage](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/chtekc5b0bdrsk4oh18x.jpg)
The Giants and Cardinals at the line of scrimmage
![Cardinals CB Patrick Peterson with the tackle](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/t7jltnsrg7owqx8zrtmp.jpg)
Cardinals CB Patrick Peterson with the tackle
![Larry Fitzgerald runs for extra yardage after the catch](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/zge6fenyhlz35fi2iaxd.jpg)
Larry Fitzgerald runs for extra yardage after the catch
![Cardinals DL Robert Nkemdiche scoops up a Giants fumble](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/zktpydwn481w14zlncfc.jpg)
Cardinals DL Robert Nkemdiche scoops up a Giants fumble
![Giants RB Shane Vereen runs while Cardinals S Budda Baker tries to bring him down](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/bqtnw9i2iop8jmocia3u.jpg)
Giants RB Shane Vereen runs while Cardinals S Budda Baker tries to bring him down
![Cardinals WR John Brown (right) celebrates with teammates after scoring a touchdown](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/susyghhsfmvnhefmqvha.jpg)
Cardinals WR John Brown (right) celebrates with teammates after scoring a touchdown
![Cardinals DL Olsen Pierre trips up Giants QB Eli Manning](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/mksdv7ig9isi9uiffda2.jpg)
Cardinals DL Olsen Pierre trips up Giants QB Eli Manning
![DL Robert Nkemdiche runs in a touchdown after a Giants fumble](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/i19lhneeuc4dfqetbxjw.jpg)
DL Robert Nkemdiche runs in a touchdown after a Giants fumble
![Cardinals QB Drew Stanton under pressure](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/qubkcrk93v5cdiqrov5j.jpg)
Cardinals QB Drew Stanton under pressure
![Giants RB Wayne Gallman on the carry](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/gpmopntziwgiify2vkiy.jpg)
Giants RB Wayne Gallman on the carry
![Cardinals DL Robert Nkemdiche scores his first career touchdown](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/wzb4wka788vpaav2gawm.jpg)
Cardinals DL Robert Nkemdiche scores his first career touchdown
![Larry Fitzgerald (left) and Eli Manning (right) meet after the game](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/ukm5oo3msrfzkozoumpx.jpg)
Larry Fitzgerald (left) and Eli Manning (right) meet after the game
![Cardinals head coach Bruce Arians (right) greets Giants interim head coach Steve Spagnuolo (left)](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/woyt2lnqy1jb7qcyncwr.jpg)
Cardinals head coach Bruce Arians (right) greets Giants interim head coach Steve Spagnuolo (left)
![Larry Fitzgerald leaves the field after the game](https://static.clubs.nfl.com/image/private/t_new_photo_album/t_lazy/f_auto/cardinals/e3fegsopylo2pspfdrhx.jpg)
Larry Fitzgerald leaves the field after the game