History: Buffalo Bills at Arizona Cardinals
- All Time Record: The Cardinals are 4-7 against the Bills in the regular season. This game is their 12th all-time meeting.
- Interesting Fact: Buffalo is one of five opponents Arizona will face that made the postseason last year – Buffalo (10-6), New England (12-4), Philadelphia (9-7), San Francisco (13-3) and Seattle (11-5). The Patriots, Eagles and 49ers each won their respective divisions in 2019.
- Streaks: The Cardinals are 3-3 all-time when hosting the Bills, including a split of the previous two meetings. The Cardinals won in 2008 and lost in 2012.
- 2016 Results: The Bills beat the Cardinals 33-18 at New Era Field in the last meeting between the two teams.
Players and Coaches to Know
Buffalo Bills
- Head Coach Sean McDermott
- Quarterback Josh Allen, Jake Fromm
Position Players John Brown, Stefon Diggs, Josh Norman - Rookies A.J. Epenesa, Zack Moss
Arizona Cardinals
- Head Coach Kliff Kingsbury
- Quarterback Kyler Murray
- Position Players DeAndre Hopkins, Larry Fitzgerald, Jordan Phillips
- Rookies Isaiah Simmons, Eno Benjamin
